I've never seen my grandparents; they died from cancer before I was born.
And I didn't even know what cancer was until my 9th-grade biology class. That was the first time I understood that biological decay is driven by entropy - the probabilistic, stochastic drift within our DNA that slowly loses order as we age.
So if that's true, why aren't we building solutions that eradicate disease and spare us from watching our pets, our loved ones, and eventually ourselves die?
The truth is that we've been trying for decades, but a fundamental flaw lies at the root of biomedical progress: we design drugs based on animals whose DNA is not our own. Drugs that "work" in rodents are not translatable to human trials.
We need something better.
Organoids arrived. They are human-derived, stem-cell-reprogrammed, three-dimensional miniature systems that model our biological systems. They eliminate the need for animal proxies and let us study human biology directly.
But organoids are stochastic by nature as well. They are inconsistent even when grown from the same protocol.
To unlock their true potential, we must build computational frameworks that reverse this chaos. Tools that turn biology from stochastic into controllable.
We start with brain organoids because the brain is the center of our consciousness and agency. It's the most critical battleground of aging. To lose control of your consciousness is to lose agency over your biological vessel.
If we can understand and predict the development of the hardest model system in existence, then everything downstream becomes possible.
And if biology becomes predictable, then medicine becomes precise. If medicine becomes precise, then aging becomes optional. And if aging becomes optional, then spiritual coping with death is no longer a necessity.
We are at war with death.
And the first step is to bring order to the chaos of human biology.